How about my order? Have my merchandise been sent already? Click here

Factor VIII

Product Description:
Factor VIII (FVIII) is an essential blood clotting factor also known as anti-hemophilic factor (AHF). In humans, Factor VIII is encoded by the F8 gene.Defects in this gene results in hemophilia A, a well known recessive X-linked coagulation disorder.
Factor VIII participates in blood coagulation; it is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids forms a complex that converts factor X to the activated form Xa. The Factor VIII gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity.
Application:
FVIII concentrated from donated blood plasma (Aafact), or alternatively recombinant FVIII can be given to hemophiliacs to restore hemostasis.
The transfer of a plasma byproduct into the blood stream of a patient with hemophilia often led to the transmission of diseases such as hepatitis B and C and HIV before purification methods were improved. Antibody formation to Factor VIII can also be a major concern for patients receiving therapy against bleeding; the incidence of these inhibitors is dependent of various factors, including the Factor VIII product itself.

Factor VIII

Send enquiry online

After send online enquiry, we will reply you as soon as possible, if not get any response on time please contact us by Tel or Email.
Email: sales@food-grade-additives.com
Tel: +86 592 5365887
WhatsApp: +86 189 6515 7632 

Please feel free to for:the product Quotation (the product price ),COA (Certificate of Analysis),New Sales Promotion,New Products,And any other assistance.

You may also be intersted in:

Serum albumin Coronin Tryptophan Serine Methionine Lysine Leucine Isoleucine

For more information of product, please send the email to sales@food-grade-additives.com.