FtsZ is a protein encoded by the ftsZ gene that assembles into a ring at the future site of the septum of bacterial cell division. FtsZ, named after "Filamenting temperature-sensitive mutant Z", is a prokaryotic homologue to the eukaryotic protein tubulin. The gene was discovered in the 1950s by Hirota and his colleagues in a screen for bacterial cell division mutants. The hypothesis was that cell division mutants of E. coli would grow as filaments due to the inability of the daughter cells to separate from one another.
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