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Protamine Other Mechanisms

It has been appropriate that the majority of anaphylactic/anaphylactoid reactions are associated with accompaniment activation and the absolution of anaphylatoxins C3a and C5a. These actuate the cyclo-oxygenase alleyway of the arachidonic acerbic metabolism in yet anonymous cells, apparently aural the lung. As a result, thromboxane and prostaglandins are released. Thromboxane is the cardinal advocate amenable for the pulmonary vasoconstriction and, presumably, aswell for the bronchospasm during Protamine reactions.

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