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Scramblase Description

Scramblase is palmitoylated and contains a potential protein kinase C phosphorylation site. Scramblase exhibits Ca2+-activated phospholipid scrambling activity in vitro. There are also possible SH3 and WW binding motifs. Scramblase is involved in the redistribution of phospholipids after cell activation or injury.

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Scramblase Description

 Scramblase is palmitoylated and contains a potential protein kinase C phosphorylation site. 

Scramblase exhibits Ca2+-activated phospholipid scrambling activity in vitro. There are also possible SH3 and WW binding motifs. Scramblase is involved in the redistribution of phospholipids after cell activation or injury .
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Tag:Scramblase  

Scramblase bochemical properties

The enzymatic action of scramblase depends on the calcium absorption present central the cell. The calcium absorption central beef is beneath accustomed altitude actual low. An access in calcium absorption activates the phospholipid busline action consistent in a symmetric administration of abnormally answerable phospholipids amid both leaflets of the lipid bilayer. The busline action of scramblase does not crave action acceptation that there is no addition of adenosine triphosphate in the process.
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Scramblase is an enzyme

Scramblase is a protein responsible for the translocation of phospholipids between the two monolayers of a lipid bilayer of a cell membrane.In humans, phospholipid scramblases (PLSCRs) constitute a family of five homologous proteins that are named as hPLSCR1–hPLSCR5. Scramblases are members of the general family of transmembrane lipid transporters known as flippases. The inner-leaflet facing the inside of the cell contains negatively charged amino-phospholipids and phosphatidylethanolamine. The outer-leaflet, facing the outside environment, contains phosphatidylcholine and sphingomyelin. Scramblase is an enzyme, present in the cell membrane, that can transport (scramble) the negatively charged phospholipids from the inner-leaflet to the outer-leaflet, and vice versa.
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